Gabriel Phthalimide Reaction

The reaction in which Phathalimide is treated with sodium hydroxide, haloalkane to produce primary aliphatic amine is known as Gabriel Phthalimide Reaction.

Pure primary amine is obtained in this reaction as its separation is easy.

NOTE-Aryl Amine can not prepared by this reaction as aryl halide does not undergo nucleophylic substitution.

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